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Entry type: Application example Entry ID: 109480213, Entry date: 12/17/2015

SIMATIC PCS 7 in the pharmaceutical industry "Freeze Dryer" (demo project)

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SIMATIC PCS 7 and SIMATIC BATCH are used to depict and control the freeze dryer process manage with the required high level of efficiency, quality and performance.

Freeze drying (lyophilization) is an important step in the production of many drugs and plays an increasingly important role in the life science industry.

It is a particularly gentle drying process which proceeds in several complex steps and has a significant impact on the quality of the end product. Therefore, to achieve a constant product quality, it is important to ensure that the necessary process conditions and parameter values are kept throughout the process.

The application example is realized as a SIMATIC PCS 7 multiproject in accordance with ISA-88 and provides a template that comprises all typical components, their open- and closed-loop control, the necessary logic and locking as well as the visualization. It is modularly structured and based on standardized equipment and control modules.

This application example contains typical equipment modules for controlling a freeze dryer. It provides configuration templates for automation tasks, such as:

  • Controlling the temperature, the pressure and the vacuum
  • Controlling the hydraulics of the shelves in the freeze dryer
  • Condenser control
  • Cleaning the freeze dryer

In the application example, the sequence of the entire process is controlled via SIMATIC BATCH.

Using the application example has the following advantages:

  • A reduction of the knowledge necessary to develop applications
  • A decrease in the configuration effort
  • More flexible setup and adaptation due to equipment modules

Further Information
Media system - Pharma Demo Applications
Application example - SIMATIC PCS 7 in the pharmaceutical industry “Blood Plasma Fractionation”
Application example - SIMATIC PCS 7 in the pharmaceutical industry “Fermentation”
Application example - PCS 7 Unit Template "CIP - Cleaning in Place"
Application example - Equipment Modules for PCS 7 using the example of the Chemical Industry


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