Is it possible to to create a control loop with a pressure transmitter as feedback?

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Split from Program pump speed via VFD with analog input device.

AutoGen_2491065

is it possible to to create a control loop (regulating speed) with a pressure transmitter as feedback using the G120 CU240B-2/CU240E-2 and no logic controller in the loop?

I'm sorry, but I don't understand what you mean.

Yes, that is possible. The drives have integrated PID controllers where you can connect a analogue input as actual value -> output goes to speed setpoint. 

ok thank you, 

how do i configure the parameters to control the speed using the pressure

i.e. for instance at pressure = 50 PSI, rpm = (X), 

and when  PSI >50 the motor decreases speed.

This FAQ manual would be a good start I think:

https://support.industry.siemens.com/cs/ww/en/view/92556266

Or you can also find information in the operation instruction manual of CU240B/E-2.