I have CP443-1 6GK7 443-1EX30-0XE0 and a CPU 410-5HX08-A0AB0CPU  v8.2

I want to configure PROFINET IO on CP 443-1. Is it possible?

When i go to in PROFINETio system it is greyed out.

Hello Session;

Based on this document for your CPU 410-5H, it can be configured as a Profinet IO Controller using its integrated Profinet ports. The CP 443-1 can be used to connect to the plant bus or the AS through TCP/IP or ISO-on-TCP, but cannot be used as a Profinet IO controller.

https://support.industry.siemens.com/cs/ww/en/view/96839331

There are various documents in the link based on various versions of PCS 7; the screenshot below is taken from version 9.0.

Hope this helps,

Daniel Chartier