Need more info. I think it is 16/21KW E/R module

What is you spindle module, post picture and post spindle control card number 

such as 6SN1118-XXXXX

AutoGen_7827197

I have a 18/21 kW power module that cannot activate the spindle drive and drive the motor, but can simultaneously drive the axes.

The voltages 24 and 15 as well as the DC link are fully present, and the orange LED on the module is on.

I replaced the module with a similar model and the problem was solved.

But I can't figure out what the problem is with this module.

Please advise me on what signal is sent from the power module to the spindle drive?

 1st of all --I found you may have SIMODRIVE 611A, 

now shut off the power disconnect flat cable take picture of spindle control card (I need to see the number 6SN1121-?????, ) BETTER THE WHOLE LABLE

2nd , when you say spindle fault what is the fault number --the fault showing on HMI of CNC and is there F0?? on the spindle card small display

3rd--let here now the story--why system like this--it working good weeks ago. suddenly faulty. or you purchased 2nd machine, power up like this?

AutoGen_7827197

 Now i understand you. you have 3rd party CNC but Siemens drive. I think your E/R module is defective --the problem is low voltage part. one of the signal from flat cable 

AutoGen_7827197

One of the machines with which the power module was tested was the Heidenhain TNC 370, which displayed a spindle drive error alarm after a rotation command, but the F*** error was not displayed on the spindle drive display.